Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)
نویسندگان
چکیده
منابع مشابه
Optimization of transplant regimens for patients with myelodysplastic syndrome (MDS).
Myelodysplastic syndrome (MDS) is a hemopoietic stem cell disorder that is potentially curable by transplantation of normal hemopoietic stem cells. The optimum timing, however, and the best conditioning strategy have remained controversial. Both conventional and reduced-intensity/nonmyeloablative regimens have been used successfully. Among selected patients with less advanced/low-risk MDS (< 5%...
متن کاملCytogenetic study of myelodysplastic syndrome from India.
BACKGROUND & OBJECTIVE Myelodysplastic syndrome (MDS) represents a group of clonal haematological disorders characterized by progressive cytopenia reflecting defects in erythroid, myeloid and megakaryocytic maturation. The incidence of MDS is more in older age groups and frequent chromosome abnormalities reported to be monosomies 5 and 7. However, the data on cytogenetic changes in Indian MDS p...
متن کاملCytogenetic Features of Elderly Turkish Myelodysplastic Syndrome Patients
Objective: Myelodysplastic syndrome (MDS) represents one of the most frequent and serious hematologic diseases among the elderly. Chromosomal abnormalities have been detected in 23%–78% patients with MDS. We analyzed the cytogenetics of elderly MDS patients in Turkey. Materials and Methods: Data on patients (>65 years old) diagnosed with primary MDS from 2011 to 2013 were retrospectively collec...
متن کاملCytogenetic profile of Indian patients with de novo myelodysplastic syndromes
BACKGROUND & OBJECTIVES Myelodysplastic syndrome (MDS) is a clonal haematopoietic stem cell disorder characterized by ineffective haematopoiesis and leukaemia progression. Cytogenetic analysis has proven to be a mandatory part of the diagnosis of MDS as well as a major indicator for predicting clinical course and outcome. Studies on cytogenetics of MDS are reported mostly from the West and only...
متن کاملMyelodysplastic syndrome (MDS) and Juvenile Myelomonocytic Leukemia (JMML)
Classification The FAB and WHO classifications The French-American-British (FAB) cooperative group produced the first systematic attempt of a classification dividing myelodysplastic syndrome (MDS) into five subgroups: refractory anemia (RA), RA with ringed sideroblasts (RARS), RA with excess of blasts (RAEB), RAEB in transformation (RAEB-t), and chronic myelomonocytic leukemia (CMML)1;2. Distin...
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ژورنال
عنوان ژورنال: Genetics and Molecular Biology
سال: 2005
ISSN: 1415-4757
DOI: 10.1590/s1415-47572005000500002